IC-P-118: βETA-AMYLOID BURDEN MODIFIES CONVERSION RISK IN CLINICALLY NORMAL AND MILD COGNITIVE IMPAIRMENT OBSTRUCTIVE SLEEP APNEA ELDERLY INDIVIDUALS
نویسندگان
چکیده
منابع مشابه
Amyloid Burden in Obstructive Sleep Apnea.
To test the hypothesis that excessive amyloid deposition is a biological link between obstructive sleep apnea (OSA) and Alzheimer's disease, we determined whether OSA increases cerebral amyloid burden, relative to controls, using Pittsburgh Compound B (PiB) PET imaging. The subjects were adult participants (age 50-65 years) from the Korean Genome and Epidemiology Study. Polysomnography, brain M...
متن کاملSerum amyloid a in obstructive sleep apnea.
BACKGROUND Patients with severe obstructive sleep apnea (OSA) may have increased risk for cardiovascular and cerebrovascular diseases. Serum amyloid A (SAA) protein has recently been linked to the development of atherosclerosis, stroke, diabetes, and dementia. We tested the hypothesis that plasma SAA levels are increased in otherwise healthy subjects with OSA. METHODS AND RESULTS Plasma SAA l...
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Older adults frequently suffer from sleep disturbances. In addition, with increasing age such disturbances may accompany mild cognitive changes that are symptomatic of a range of neurodegenerative conditions. There is increasing evidence that sleep may represent a prodromal symptom, risk factor or agitator of further decline in cognitive functioning of the older adult. Current research is focus...
متن کاملA survey on the relationship between obstructive sleep apnea and difficult intubation in the elderly
Background and Objectives: Difficult intubation is one of the challenges for patients undergoing anesthesia that leads to severe complications and death. Obstructive sleep apnea is one of the factors that may be associated with difficult intubation. The present study was carried out to investigate the relationship between obstructive sleep apnea and difficult intubation in the elderly. Mater...
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OBJECTIVES Sleep apnea syndrome (SAS) is considered a risk factor for cognitive decline in the elderly. The specific neurocognitive decline has been suggested as a predictive factor for dementia in patients with mild cognitive impairment (MCI). The authors aim to illustrate the sleep characteristics related to the specific neurocognitive decline in the community-dwelling elderly including patie...
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ژورنال
عنوان ژورنال: Alzheimer's & Dementia
سال: 2019
ISSN: 1552-5260
DOI: 10.1016/j.jalz.2019.06.4232